منابع مشابه
Myeloma Cells with Auer Rod-like Inclusions
The presented image showings heavily granulated myeloma cells, some with Auer rod-like inclusions. Auer rod-like inclusions in myeloma are composed of crystallized lysosomal enzyme depositions. They are distinguished from intracytoplasmic immunoglobulin crystals. The factors that predispose to Auer rod-like inclusions in myeloma are unknown; however, in all reported cases paraprotein was of the...
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The nucleus is the center of vital activity and is the brain of any cell. This stands true in case of physiological and pathological cells. Nucleus is the most active and prominent cellular organelle which shows many forms, has varied shapes and sizes, depicting the activity of the cell. Morphology of the nuclear shape and presentation can get altered because of changes in nuclear lamina or it ...
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This short report discusses a case of neurofibroma containing floret-like multinucleated giant cells. This being the second such case in the literature. Floret-like multinucleated giant cells have been reported in gynaecomastia and neurofibroma in neurofibromatosis type 1. These cells have been reported in uncommon soft tissue tumours including pleomorphic lipoma, giant cell collagenoma, giant ...
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Signet-ring cells, typical of muciparous adenocarcinoma, are seldom observed in other solid tumors or in lymphoproliferative disorders. Two cases of myeloma with signet-ring morphology have been reported so far. To the best of our knowledge, the following is the first case of signetring cell Bence-Jones myeloma. A 69-year-old man presented with cachexy, dehydration, liver enlargement and multin...
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Multiple myeloma (MM) is a plasma cell malignancy affecting the bone marrow (BM); despite the introduction of novel therapies, 490% of the MM patients relapse owing to drug resistance and microresidual disease. Relapse and microresidual disease in MM may be attributed to the development of a stem cell-like subpopulation, which demonstrates resistance to therapy and causes recurrence. In solid t...
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ژورنال
عنوان ژورنال: American Journal of Hematology
سال: 2004
ISSN: 0361-8609,1096-8652
DOI: 10.1002/ajh.20246